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PRP-Platelet Rich Plasma

The Selphyl® System is designed for the safe and rapid preparation of Platelet-rich Fibrin Matrix (PRFM) from a small sample of blood at the patient point of care. Many PRP systems require operator skill, have varying results and have extensive contamination with red blood cells and white blood cells. Selphyl® removes virtually all contaminating cells and is independent of operator technique. PRP is converted to PRFM through a controlled process, creating a scaffold that serves to protect and preserve platelets. Think of Selphyl® PRFM as the next generation PRP.

HOW IS SELPHYL® PLATELET-RICH FIBRIN MATRIX (PRFM) DIFFERENT?

The Selphyl® System is a completely closed system and can convert PRP to PRFM with the addition of a precise amount of calcium chloride, which initiates the conversion of fibrinogen to fibrin, as part of the clotting cascade. The fibrin matrix serves as a three-dimensional scaffold to maintain the platelets at the site of application. The
scaffold also serves to protect the platelets so their release of growth factors can be sustained over a
longer period of time.

PLATELET CONCENTRATION

selphyl prpIn order for the growth factor benefits to be harnessed they must be isolated intact. A distinguishing feature of the kit system is the use of a thixotropic gel separator. This gel allows for the ideal concentration factor of 1.6 fold the patient’s baseline to be prepared, resulting in an optimal platelet recovery upwards of 80%. Although the system is capable of yielding a higher platelet concentration, the concentration of 1.6 fold has been clinically proven to be effective in various published studies for different indications.

APPLICATION

The use of Platelet Rich Plasma has been evaluated in clinical studies across various medical disciplines.

The kit product family is indicated by the US FDA for the safe and rapid preparation of Autologous-Platelet Rich Plasma (A-PRP) from a small sample of blood at the patient’s point of care. The A-PRP is mixed with autograft and / or allograft bone prior to application to a bony defect for improving handling characteristics.
The kit family kits are for single use only.